Verbal processing deficits in schizophrenia

Author(s): Donegan, N. H., Anderson, M., GoldmanRakic, P. S., Wexler, B. E.

Journal/Book: J Abnormal Psychol. 2000; 109: 750 First St NE, Washington, DC 20002-4242, USA. Amer Psychological Assoc. 461-471.

Abstract: The authors reported that a subgroup of schizophrenic patients performed well on a tone serial position task but was impaired on an auditory word serial position task (Wexler, Stevens, Bowers, Cerniak, & Goldman-Rakic, 1998). This study assessed 30 schizophrenic and 32 controls (matched for comparable tone discrimination) on 4 versions of the verbal serial position tasks and 2 tone serial position tasks. Patients performed poorly on all verbal tasks but performed comparably to controls when tones served as stimuli. Proactive interference and visual presentation further compounded the verbal deficits. Deficits persisted with pronounceable nonword stimuli. These findings provide evidence of specific deficits in language-related processing, although the authors could not rule out the possibility that the differential effects that were observed between the tone and word tasks, and particularly among. The verbal tasks, may result from differing discriminating power of the different tests.

Note: Article Stevens AA, Oregon Hlth Sci Univ, Dept Psychiat, CR139, 3181 SW Sam Jackson Pk Rd, Portland,OR 97201 USA

Keyword(s): SHORT-TERM-MEMORY; WORKING-MEMORY; PROACTIVE-INTERFERENCE; SELECTIVE IMPAIRMENT; THOUGHT-DISORDER; WORD; DYSFUNCTION; SPEECH; PERFORMANCE; RECALL

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