CAMCOG as a screening instrument for dementia: the Odense Study

Author(s): Nielsen, H., Andersen, K., Andersen, J., KraghSorensen, P.

Journal/Book: Acta Psychiat Scand. 2000; 102: 35 Norre Sogade, PO Box 2148, Dk-1016 Copenhagen, Denmark. Munksgaard Int Publ Ltd. 331-335.

Abstract: Objective: The Cambridge Cognitive Examination (CAMCOG) score is correlated with age and sociodemographic variables. The aim of the study was to determine an individualized CAMCOG cut-off score for dementia, taking such correlates into account. Method: From the general population 150 people aged 65-84 years were examined with CAMDEX which includes CAMCOG, and a neuropsychological test battery. Data from 130 non-demented people were entered in setwise multiple regression analyses to identify variables predicting the CAMCOG score. Results: The variables age, social class, matrimonial status, general knowledge ar id intellectual level explained 66% of the variance of the CAMCOG scores. A cut-off defined as a difference between actual and predicted CAMCOG score less than or equal to -4.41 resulted in a sensitivity of 88.2% and a specificity of 89.2% for very mild to moderate dementia. Conclusion: It is possible to determine an individualized CAMCOG cutoff score for dementia in its early stages.

Note: Article Lolk A, Odense Univ Hosp, Dept Psychiat, DK-5000 Odense C, DENMARK

Keyword(s): screening; dementia; sensitivity; specificity; PSYCHOMETRIC PROPERTIES; ALZHEIMERS-DISEASE; NORMATIVE DATA; DIAGNOSIS; DENMARK; CAMDEX; SAMPLE; MILD

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