Zhong Yao Cai. 1999 Oct; 22(10): 520-3.

[Supercritical-CO2 fluid extraction of fatty oils from Perilla frutescens seeds and pharmacological study]

Tan X, Yie L, Ge F.

Guangzhou Pharmaceutical Industrial Research Institute, Guangzhou 510240.

Fatty oils from the seeds of Perilla frutescens were extracted by supercritical-CO2 fluid or petroleum ether and its quality was analyzed by GC-MS method. Pharmacological action of lowering blood-lipid for the oils was studied. The results showed that the technology of supercritical-CO2 extraction of the oils of P. frutescens seeds is superior than that of petroleum ether and the oil from SFE-CO2 have the action of lowering blood-lipid with low toxicity.