Zhongguo Zhong Xi Yi Jie He Za Zhi. 1999 Mar; 19(3): 144-7.

[Clinical study on hyperthyroidism of yang hyperactivity type due to yin deficiency treated by jiakang ning capsule]

Lin L, Li M, Liu X.

Guang'anmen Hospital, China Academy of Traditional Chinese Medicine, Beijing (100053).

OBJECTIVE: To investigate the effect of Jiakang Ning (JKN) capsule on hyperthyroidism. METHODS: Eighty-five cases of hyperthyroidism were divided into JKN group (24 cases), JKN with low dose Tapazol group (35 cases) and Tapazol control group (26 cases) at random. The effects were evaluated by total effective rate, using principal symptoms, body weight, EKG, thyroid hormone and atrial natriuretic peptide (ANP) after 6 months. RESULTS: The total effective rates of three groups were 83.8%, 97.1%, 88.5% respectively, and there were insignificant difference among them statistically (P > 0.05). The first two groups had better effect in principal symptoms than Tapazol control group (P < 0.05). There were similar results in adjusting thyroid dysfunction and abnormal EKG, decreasing ANP and increasing body weight among those three groups (P > 0.05). CONCLUSION: The effect on hyperthyroidism treatment by JKN capsule was satisfactory. The combination of Chinese herbs with western medicine could enhance the curative effect of hyperthyroidism without obvious side-effects.