Zhongguo Zhong Xi Yi Jie He Za Zhi. 1999 Oct; 19(10): 595-8.

[Clinical and experimental study on treatment of Helicobacter pylori infected gastritis by xialian yiyou capsule]

Ji A, Zhao W, Wang Z.

First Affiliated Hospital of Henan College of TCM, Zhengzhou (450000).

OBJECTIVE: To observe the therapeutic effect of Xialian Yiyou Capsule (XLYYC) on helicobacter pylori (HP) infected gastritis to develop the serial Chinese classical recipe. METHODS: HP infected patients were divided into two groups, 136 patients in the XLYYC group treated with XLYYC and 90 patients in the control group treated with Lizhu Dele Capsule, for 4 weeks as one therapeutic course, the clinical therapeutic effect was observed, and corresponding animal experiments were done. RESULTS: Clinical effect of the XLYYC group was better than that of the control group in improving clinical symptoms, relieving inflammation of gastric mucosa and eliminating HP (P < 0.05, P < 0.01). Results of animal experiment showed that XLYYC was superior than the control significantly in anti-inflammation, analgesia, stomach emptying and curing gastric ulcer model (P < 0.05, P < 0.01). Without any adverse reaction has been found in acute toxicologic study. CONCLUSION: The therapeutic effect of XLYYC in treating HP infected gastritis was definite and safe, non-toxic.