Phytother Res. 1999 Dec; 13(8): 680-2.

Screening of Korean plants against human immunodeficiency virus type 1 protease.

Min BS, Bae KH, Kim YH, Miyashiro H, Hattori M, Shimotohno K.

College of Pharmacy, Chungnam National University, Taejon 305-764, Korea.

With the aim of finding novel anti-human immunodeficiency virus agents from natural products, 93 MeOH extracts of Korean plants were screened for their inhibitory activities against HIV-1 protease. The most potent inhibition was shown by the root of Rodiola rosea with 70.4% inhibition at a concentration of 100 microg/mL.Copyright 1999 John Wiley & Sons, Ltd.