J Ethnopharmacol. 1999 Sep; 66(3): 355-61.

Hepatoprotective activity of leaves of Cassia occidentalis against paracetamol and ethyl alcohol intoxication in rats.

Jafri MA, Jalis Subhani M, Javed K, Singh S.

Department of Ilmul Advia, Faculty of Medicine(Unani), Jamia Hamdard, New Delhi, India.

Cassia occidentalis L. (Caesalpiniaceae), commonly known as 'Kasondi', is used in Unani medicine for liver ailments and is an important ingredient of several polyherbal formulations marketed for liver diseases. The hepatoprotective effect of aqueous-ethanolic extract (50%, v/v) of leaves of kasondi was studied on rat liver damage induced by paracetamol and ethyl alcohol by monitoring serum transaminase (aspartate amino transferase and serum alanine amino transferase), alkaline posphatase, serum cholesterol, serum total lipids and histopathological alterations. The extract of leaves of the plant produced significant hepatoprotection.