Indian J Exp Biol. 1999 Jan; 37(1): 27-31.

Effect of "rasayanas", a herbal drug preparation on immune responses and its significance in cancer treatment.

Kumar VP, Kuttan R, Kuttan G.

Amala Cancer Research Centre, Amala Nagar, Thrissur, India.

Rasayanas are considered to be immunostimulating preparations used extensively in indigenous medical practice. However there are only very few reports to substantiate this claim, and this paper gives preliminary evidence for the potentiation of immunity by Rasayanas given to mice orally. Administration of Rasayanas were found to enhance the proliferation of spleen cells significantly especially in the presence of mitogen. Similar result was also seen with bone marrow cells; however mitogenic stimulation could not be observed. Esterase activity was found to be enhanced in bone marrow cells indicating increased maturation of cells of lymphoid linkage. Rasayanas also enhanced humoral immune response as seen from the increased number of antibody forming cells and circulating antibody titre. These results indicate the usefulness of Rasayana as immunostimulating agent.