Proc Soc Exp Biol Med. 1999 Apr; 220(4): 229-33.

Inhibitory effect of green and black tea on tumor growth.

Conney AH, Lu Y, Lou Y, Xie J, Huang M.

Laboratory for Cancer Research, Department of Chemical Biology, College of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854-8020, USA.

The administration of green tea, black tea, or (-)-epigallocatechin gallate inhibited the growth of established nonmalignant and malignant tumors in tumor-bearing mice. In experiments with black tea, we found that its oral administration inhibited DNA synthesis and enhanced apoptosis in both nonmalignant and malignant tumors in tumor-bearing mice.