Non-ginsenoside nicotinic activity in ginseng species

Author(s): Lewis, R., Wake, G. , Court, G. , Pickering, A. T. , Kim, Y. C. , Perry, E. K.

Journal/Book: Phytother Res. 1999; 13(1): 59-64.

Abstract: Amongst the many different therapeutic applications of ginseng are beneficial effects on age-related cognitive impairments. Ageing in the brain is associated with a loss of nicotinic receptor binding and receptor stimulation increases binding. Stimulation of the CNS (central nervous system) nicotinic receptor is considered to be beneficial in relation to symptomatic treatment and neuroprotection in age-associated cognitive disorders which involve a further hemical constituent has yet to be identified, but the demonstrated nicotinic activity of ginseng warrants further investigation with reference to therapeutic activity in age-related conditions such as dementia.

Keyword(s): phyto. br. ginseng.

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