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October 2021

Status of Clinical Knowledge on Vitex agni-casti fructus

Abstract: The dopaminergic effect of different extracts of Vitex agnus-castus has been proven in several clinical and pharmacological studies. In this article, various open studies of different indications concerning cycle disorders, one double-blind study of luteal phase defect and two double-blind studies an patients suffering from mastodynia ere described and discussed. Also, the dopaminergic effect of extracts of Vitex agnus-castus an male test persons is examined. The results received with the open studies as well as the double-blind studies confirm the field of application of Agni-casti-fructus preparations as recommended by German’s Commission E.

Keyword(s): Vitex agnus-castus

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