Traditional Remedies and Food Supplements

Author(s): Leon, C., Kolev, S., Murray, V.

Abstract: Since 1991, the Medical Toxicology Unit (MTU) at Guys Hospital, London, has been assessing the toxicological problems associated with the use of traditional and herbal remedies and dietary supplements. This assessment was carried out by evaluating reports to the National Poisons Information Service (London) [NPIS(L)] which provides emergency information to medical professionals. Relevant Telephone enquiries to NPIS (L) were identified. Further case details were obtained by follow-up questionnaire, clinical consultation, toxicological analysis of samples from patients and/or products and botanical identification of plant materialOf 1297 symptomatic enquiries evaluated, there was a possible/confirmed association of 785 cases. Case series have been identified which substantiate previous reports, including liver problems following the use of Chinese herbal medicine for skin disorders, allergic reactions to royal and propolis and heavy metal poisoning caused by remedies from the lndian subcontinent. Although the overall risk to public health appears to be low, certain groups of traditional remedies have been associated with a number of potentially serious adverse effects.Considering the extent of use of herbal remedies and food supplements, 0 comprehensive surveillance system for monitoring the adverse health effects of these products is essential. Surveillance of a large population is needed for the complex task of identifying the uncommon and unpredictable adverse effects which are potentially serious. In the UK, the Medicines Control Agency responded to the MTU report by recognising the need for vigilance and by incorporating adverse reactions reporting an unlicensed herbal remedies into their drug reaction monitoring function. As a further step to safeguard the patients/consumers, an effective single regulatory system is required which would ensure the safety and quality of all herbal remedies and food supplements available in the UK.

Keyword(s): Herbal remedies

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