Salud Publica Mex. 1998 Jul-Aug; 40(4): 354-8.
[Hypoglycemic activity of Bouvardia terniflora, Brickellia veronicaefolia, and Parmentiera edulis]
Laboratorio de InvestigaciÃ³n de Productos Naturales, Escuela Superior de IngenierÃa QuÃmica e Industrias Extractivas, Instituto PolitÃ©cnico Nacional, MÃ©xico, D.F., MÃ©xico.
OBJECTIVE: To evaluate the hypoglycemic activity of the hexane, chloroform and methanol extracts of Bouvardia terniflora, Brickelia veronicaefolia and Parmentiera edulis. MATERIAL AND METHODS: Normal and alloxan-induced diabetic mice were administered these plant extracts (intraperitoneal 100, 200 and 300 mg/kg). RESULTS: The administration of 300 mg/kg of chloroform extracts from P. edulis and B. terniflora and hexane from B. veronicaefolia to diabetic mice decreased the blood glucose levels in 43.75, 58.56 and 72.13%, respectively. These extracts administered to normal mice reduced blood glucose levels in 29.61, 33.42 and 39.84%, respectively. CONCLUSIONS: The hypoglycemic effect of these plant extracts used in traditional medicine for diabetes treatment is confirmed.