J Ethnopharmacol. 1998 Jun; 61(2): 161-6.

Antiinflammatory and antioxidant activity of plants used in traditional medicine in Ecuador.

de las Heras B, Slowing K, BenedÃ J, Carretero E, Ortega T, Toledo C, Bermejo P, Iglesias I, Abad MJ, GÃ³mez-Serranillos P, Liso PA, Villar A, Chiriboga X.

Departamento de FarmacologÃa, Facultad de Farmacia, Universidad Complutense de Madrid, Spain.

Ethanolic extracts from 15 plant species, representing eight different families, used in traditional medicine in Ecuador were evaluated for antiinflammatory and antioxidant activities. Conyza floribunda, Eupatorium articulatum, Bonafousia longituba, Bonafousia sananho, Tagetes pusilla and Piper lenticellosum extracts showed a significant antiinflammatory activity in vivo in the carrageenan-induced paw oedema model in mice. The extracts were also tested in vitro for their ability to inhibit lipid peroxidation and to scavenge superoxide and hydroxyl radicals. E. articulatum extract possesses both activities. Baccharis trinervis, E. articulatum and Phytolacca rivinoides extracts were active as antioxidants.