Treatment of rheumatoid arthritis with a peptide diet : A randomized, controlled trial

Author(s): Holstjensen, S., Pfeifferjensen, M. , Monsrud, M. , Tarp, U. , Buus, A. , Hessov, I. , Thorling, e. , Stengaardpedersen, K.

Journal/Book: Scand J Rheumatol. 1998; 27(5): 329-336.

Abstract: Elemental diets provide food in its simplest formulation and have been used in the treatment of rheumatoid arthritis (RA) and other chronic inflammatory diseases. Such a diet is supposed to be less antigenic to the human immune system than normal food. The aim of this study was to evaluate the clinical effect of an artificial peptide diet as a temporary supplement to conventional treatment. Patients with active RA were single-blindly randomized either to a liquid elemental peptide-diet for four weeks or to continuation of the usual food (control group). In the diet group all normal foods were renounced. Thirty patients were included and followed for six months. The outcome measurem he diet group had a clear remission. Side-effects were frequent but compliance good. ht be beneficial to a subset of RA-patients, e.g. patients where foods aggravate disease activity.

Keyword(s): cam. cr. rct. rheum. diet

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