Observations on the relationship between verbal explicit and implicit memory and density of neurons in the hippocampus

Author(s): Esiri, M. M., Beardsworth, E. D.

Journal/Book: Neuropsychologia. 1998; 36: The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, England. Pergamon-Elsevier Science Ltd. 1049-1062.

Abstract: The relationship between neuronal density and verbal memory in left and right hippocampal subfields was investigated in patients who underwent surgery for alleviation of temporal lobe epilepsy. The surgery consisted of unilateral partial removal of the hippocampus along with the anterior temporal lobe and amygdala. Study 1 looked at post-surgical explicit vs implicit verbal memory for lists of words while Study 2 looked at pre- and post-surgical explicit memory for word pairs. Left subfield CA1 appeared to be the most consistently involved in explicit and implicit memory. The results of the two studies confirm presence of hemispheric asymmetry in verbal memory. The notion that hippocampal control of memory is most apparent in post-surgical performance is discussed.

Note: Article Zaidel DW, Univ Calif Los Angeles, Dept Psychol, 1282A Franz Hall, Box 951563, Los Angeles,CA 90095 USA

Keyword(s): epilepsy; CA1; human; plasticity; mind-brain; hemispheric specialization; ANTERIOR TEMPORAL LOBECTOMY; PYRAMIDAL CELL-DENSITY; BRAIN INJURY; EPILEPTIC PATIENTS; LOBE EPILEPSY; FOLLOW-UP; SURGERY; AGE; CONNECTIONS; RECOGNITION

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