The clinical utility of randomized controlled trials

Journal/Book: Int J Eating Disorder. 1998; 24: 605 Third Ave, New York, NY 10158-0012. John Wiley & Sons Inc. 13-29.

Abstract: Objective: Efficacy studies using randomized controlled trials (RCTs) on which empirically supported treatments are based, are often rejected as having little if any relevance to clinical practice. RCTs are faulted for allegedly excluding poor prognosis patients and therapists and treatments that are unrepresentative of clinical practice. Methods: Evidence on the generalizability of findings from RCTs to diverse patient populations, different therapists, and varied clinical settings is critically evaluated. Results: Existing research indicates that RCTs commonly include patients with multiple problems and levels of disturbance as severe as patients in clinical settings. Discussion: The applicability of the findings of RCTs to clinical practice will be a changing function of the nature of the particular study and clinical setting to which the results are to be generalized. Future research should address the clinical utility of the findings of efficacy studies across different patient populations, therapists, and treatment methods.

Note: Article Wilson GT, Rutgers State Univ, Grad Sch Appl & Profess Psychol, POB 819, Piscataway,NJ 08855 USA

Keyword(s): controlled trials; bulimia nervosa; efficacy studies; COGNITIVE-BEHAVIORAL TREATMENT; 3 PSYCHOLOGICAL TREATMENTS; BULIMIA-NERVOSA; PERSONALITY-DISORDER; ANXIETY DISORDERS; PANIC DISORDER; PRIMARY-CARE; INTERPERSONAL PSYCHOTHERAPY; ADOLESCENT PSYCHOTHERAPY; MAJOR DEPRESSION

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