Alcohol hangover - Mechanisms and mediators

Author(s): Davidson, D.

Journal/Book: Alcohol Health Res World. 1998; 22: 6000 Executive Blvd, Rockville, MD 20892-7003, USA. Natl Inst Alcohol Abuse Alcoholism. 54-60.

Abstract: Hangovers are a frequent, though unpleasant, experience among people who drink to intoxication. Despite the prevalence of hangovers, however, this condition is not well understood scientifically. Multiple possible contributors to the hangover state have been investigated and researchers have produced evidence that alcohol can directly promote hangover symptoms through its effects on urine production, the gastrointestinal tract, blood sugar concentrations, sleep patterns, and biological rhythms. In addition, researchers postulate that effects related to alcohol's absence after a drinking bout (i.e., withdrawal), alcohol metabolism, and other factors (e.g, biologically active, nonalcohol compounds in beverages; the use of other drugs; certain personality traits; and a family history of alcoholism) also may contribute to the hangover condition. Few of the treatments commonly described for hangover have undergone scientific evaluation.

Note: Article Swift R, Brown Univ, Dept Psychiat & Human Behav, Providence,RI 02912 USA

Keyword(s): post AOD intoxication state; symptom; urinalysis; gastrointestinal disorder; hypoglycemia; sleep disorder; circadian rhythm; ethanol metabolite; disorder of fluid or electrolyte or acid-base; balance; nutrient intake; headache; vomiting; neurotransmitter receptors; congenors; multiple drug use; personality trait; family AODU (alcohol and other drug use) history; drug therapy; literature review; WITHDRAWAL; SYMPTOMS; PERSONALITY; POPULATION; ETHANOL; SIGNS; SONS

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