J Ethnopharmacol. 1997 May; 56(3): 223-6.

Chemical composition and antimicrobial activity of Croton urucurana Baillon (Euphorbiaceae).

Peres MT, Delle Monache F, Cruz AB, Pizzolatti MG, Yunes RA.

Departamento de Ciencias BiolÃ³gicas, Universidade Federal de Mato Grosso do Sul, Centro UniversitÃ¡rio, Dourados, MS, Brazil.

In the methanolic extract of Croton urucurana Baillon (Euphorbiaceae) a number of known compounds, such as acetyl aleuritolic acid, stigmasterol, beta-sitosterol, campesterol, beta-sitosterol-O-glucoside, sonderianin, catechin and gallocatechin were isolated and identified by MS and NMR spectroscopy, HRGC and data from literature. The antibacterial activity of the aqueous-EtOH extract, some fractions of the methanolic extract and some of the isolated compounds, were tested against Staphylococcus aureus and Salmonella typhimurium. Acetyl aleuritolic acid exhibits the best minimum inhibitory concentration (MIC) against both Staphylococcus aureus and Salmonella typhimurium.