Zhong Yao Cai. 1997 Jan; 20(1): 38-40.

[Preliminary study on the pharmacological action spicatus]

Gai H, Shou Y, Wang J, Li L.

Zhejiang Acedemy of Medical Sciences, Hangzhou 310013.

In this report the pharmacological action of Spicatus was studied. The results insicated that it had diureric, antibiotic and anti-inflammatory effects, yet had Iittle toxic side-effect. It had significant inhibitory effect on crofon oil-caused mice ear swell. It also had marked diuretic effect in orcinary rats, but had Iittie effect on uric pH the rats. It exhibited certain inhibition of Staphycoloccus aureus, Eschrichia coli and Pseudomonas aeruginosa in vitro. The maximum tolerable dose test in mice showed no marked toxic effect, LD50 > 80 g/kg.