Zhongguo Zhong Xi Yi Jie He Za Zhi. 1997 Jul; 17(7): 390-2.

[Treatment of integrated traditional and Western medicine in recurrent spontaneous abortion of immune abnormality type]

Li DJ, Li CJ, Zhu Y.

Laboratory of reproductive Immunology, Shanghai Medical University.

Immune abnormality type of recurrent spontaneous abortion (RSA) is an important etiological type, major findings of that are the abnormal increases in auto and/or allo-antibodies of anti-zona pellucida, antiphospholipid and anti-ABO blood group. In the present study, to assess the clinical values of integrated traditional and Western medicine and its therapeutic mechanisms in treating immune abnormality type of RSA. METHODS: Aborters were treated by Zhibai Dihuang Pills for anti-zona pellucida antibodies, and clear evil Heat, remove Dampness, replenish blood and activate circulation by Chinese medicinal herbs recipe for anti-phospholipid and anti-ABO group antibodies. RESULTS: After they had been treated by these recipe, 92.3% of them became pregnant with normal delivery. It was found in dynamic investigation that level of the antibodies turned to decrease gradually during the treatment, and that of anti-phospholipid and anti-ABO group antibodies increased again at beginning of pregnancy and then decreased gradually with continuing pregnancy. CONCLUSION: Chinese herbs recipe could be used to treat RSA of the immune abnormality type by way of decreasing the elevated levels of auto and/or allo-antibodies.