Memory consolidation in Drosophila operant visual learning

Author(s): Liu, L., Feng, C. H., Guo, A.

Journal/Book: Learn Memory. 1997; 4: 1 Bungtown Rd, Plainview, NY 11724. Cold Spring Harbor Lab Press. 205-218.

Abstract: A near conditioning procedure, developed for the operant learning paradigm at the flight simulator, leads to stronger learning scores in wild-type flies. This procedure produces mean learning indices up to LI = 0.52. The heat-avoidance behavior acquired during training is very difficult to extinguish during extinction. Memory decays quickly during the first 3 hr after training and still is measurable 48 hr later, Disruption experiments demonstrate that memory can be disrupted by cold anesthesia within the first similar to 20 min after training, whereas KCl- and CXM-feeding regimens abolish memory soon after training and 3 hr later, respectively. These results initially suggest at least three distinct memory phases involved in memory consolidation in Drosophila after operant conditioning.

Note: Article Guo A, Acad Sinica, Inst Biophys, Lab Visual Informat Proc, Beijing 100101, PEOPLES R CHINA

Keyword(s): LONG-TERM-MEMORY; DEFENSIVE WITHDRAWAL REFLEX; MUTANT DROSOPHILA; SENSORY NEURONS; CELLULAR MECHANISM; FLIGHT ORIENTATION; MELANOGASTER; BEHAVIOR; APLYSIA; RETENTION

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