Current controversies and future directions in basal ganglia research - Integrating basic neuroscience and clinical investigation

Author(s): Miguel, E. C., Rauch, S. L., Leckman, J. F.

Journal/Book: Psychiat Clin N Amer. 1997; 20: Independence Square West, Curtis Center, Ste 300, Philadelphia, PA 19106-3399. W B Saunders Co. 945.

Abstract: This article discusses current controversies and future directions in basal ganglia research, detailing behavioral aspects, anatomic models, neurochemistry, pharmacology, and diagnostic methods as well as surgical techniques. A neuroethologic perspective is highlighted. Furthermore, the relevant literature pertaining to contemporary molecular approaches such as brain microinjections of embryonic or genetically modified cells, for therapeutic purposes and the use of transgenic and knockout animals.

Note: Review GarciaCairasco N, Univ Sao Paulo, Ribeirao Preto Sch Med, Dept Physiol, Neurophysiol & Expt Neuroethol Lab, BR-14049900 Ribeirao Pret, BRAZIL

Keyword(s): PRIMATE SUBTHALAMIC NUCLEUS; OBSESSIVE-COMPULSIVE DISORDER; TEMPORAL-LOBE ONSET; PARKINSONS-DISEASE; SUBSTANTIA-NIGRA; NEURONAL-ACTIVITY; AUDIOGENIC-SEIZURES; WISTAR RATS; MPTP MODEL; IRON

Zurück | Weiter