Relationships between symptoms of schizophrenia and substance abuse

Author(s): Mueser, K. T., Xie, H. Y., Drake, R. E.

Journal/Book: J Nerv Ment Dis. 1997; 185: 351 West Camden St, Baltimore, MD 21201-2436. Williams & Wilkins. 13-20.

Abstract: Previous work posits that severity of substance abuse and severity of schizophrenic symptoms should be linked by either or both of two mechanisms: self-regulation of symptoms and drug-induced exacerbation of symptoms. Research on these relationships has yielded mixed results. We examined the interrelationships of schizophrenic symptoms and substance abuse in 172 patients with co-occurring disorders. Relationships were weak or nonexistent, without any consistent pattern. Our findings do not support the view that substances are used to self-regulate symptoms. In addition, our results suggest that substance abuse may lead to higher rates of institutionalization through mechanisms other than by exacerbating symptoms.

Note: Article Drake RE, Dartmouth Coll Sch Med, New Hampshire Dartmouth Psychiat Res Ctr, 105 Pleasant St, Concord,NH 03301 USA

Keyword(s): SEVERE MENTAL-ILLNESS; USE DISORDERS; ALCOHOL-USE; REVOLVING-DOOR; COCAINE USE; DRUG-ABUSE; COMMUNITY; CANNABIS; FAMILY; NEUROLEPTICS

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