Magnetoencephalographic evidence for common sources of long latency fields to rare target and rare novel visual stimuli

Author(s): Rogers, R. L., Simos, P. G., Papanicolaou, A. C.

Journal/Book: Int J Psychophysiol. 1997; 25: PO Box 211, 1000 AE Amsterdam, Netherlands. Elsevier Science BV. 123-137.

Abstract: This study used magnetoencephalography to examine the possibility that different generators account for the long-latency event-related potential (P300), evoked by rare target and by rare non-target, novel visual stimuli, in a visual oddball counting task performed by seven subjects. As expected, P300 peak latency was longer in response to rare targets compared to novel, non-target stimuli. Two main source regions were found for the Target- as well as for the Novel-P300, one in the temporal and one in the occipital lobe. Centers of neural activity were observed in the vicinity of the superior temporal sulcus, in the hippocampal formation and parahippocampal gyrus and in the occipital extrastriate cortex. It appears that the brain structures which contributed to the generation of the P300 response to both the target and the novel visual stimuli overlapped to a great extend.

Note: Article Basile LFH, Univ Texas, Hlth Sci Ctr, Dept Neurosurg, 6431 Fannin, Suite 7148, Houston,TX 77030 USA

Keyword(s): magnetoencephalography; evoked potential; novelty; oddball paradigm; superior temporal sulcus; POSITIVE EVOKED-POTENTIALS; EVENT-RELATED POTENTIALS; MEDIAL TEMPORAL-LOBE; MAGNETIC-FIELDS; AUDITORY-STIMULI; TASK-RELEVANCE; RHESUS-MONKEY; CORTEX; P300; MEMORY

Zurück | Weiter