Metabolic and renal changes following the ingestion of African mistletoe extract in rats

Journal/Book: Phytother-Res. 11 (2), 171-173. 1997;

Abstract: The effect of an aqueous extract of African mistletoe (Loranthusbegwensis) from two host plants (Citrus limon (Cl-mistletoe) or Vernoniaamygdalina (Va-mistletoe)) was studied in male Wistar rats treatedorally with either 1.32, 13.2 or 26.4 g/kg per day for 7 days. Asignificant dose-dependent reduction (p < 0.01) in the serum glucose andcholesterol was obtained with both extracts, accompanied by a reductionof mine flow rate and serum creatinine. Increases in urinary enzymes andprotein excretion were dose-related and dependent on the source ofextracts. Mistletoe extract irrespective of source appears to lower theblood sugar level offering the potential for clinical use of theingredients of its extracts.COPYRIGHT BY Elsevier Science BV, Amsterdam, Netherlands END OF DOCUMENT

Keyword(s): Medical:hypoglycemia

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