Celandine - Chelidonium majus L.

Abstract: The use of preparations from celandine for the treatment of cramp-like complaints of the bile- and gastrointestinal tract has been unchanged since ancient times. The effects of celandine extracts could be proven recently by means of experimental and clinical studies performed according to rational phytotherapeutical measures. Standardized celandine preparations are highly appreciated by general physicians.Because coptisine, located in the herb and chelidonine, located in the roots, represent the main alkaloids and because both alkaloids are responsible for the effectiveness of the drug, a characterization of industrial celandine extracts is necessary.The alkaloids from Chelidonium majus in several test models exhibit differing spasmolytic effects. The actual pharmacopoe-monograph should be revised concerning the prescribed time of harvesting and concerning the testing for identity by means of TLC.

Keyword(s): Chelidonium majus L.

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