Zhen Ci Yan Jiu. 1996 ; 21(4): 25-7.

[Effects of electrical stimulation of SII and electroacupuncture on beta-endorphin contents in the perfusate from the nucleus centrum medianum of the thalamus in cats]

Dong X, Wang S, Wang Y.

Institute of Acupuncture and Moxibustion, China Academy of TCM, Beijing.

In order to probe into whether beta-endorphin is involved in descending modulation of the somatosensory area (SII) of the cerebral cortex on the nucleus centrum medianum (CM) of the thalamus and this mechanism of acupuncture analgesia, it was investigated that effects of electrical stimulation of SII and electroacupuncture on beta-endorphin content in the perfusate from the nucleus CM. Adult cats were randomly divided into three groups: control, electroacupuncture and electrical stimulation of SII. Push-pull perfusion technique was used to collect the perfusate from the nucleus CM beta-endorphin contents in the perfusate were determined with radioimmunoassay. The results indicated that beta-endorphin content in the perfusate was increased significantly by electrical stimulation of SII and not by electroacupuncture, suggesting that the beta-endorphin release from the nucleus CM was elevated by the stimulation of SII and was not influenced by electroacupuncture. It is indicated that beta-endorphin is possibly involved in the descending regulatory effect of electrical stimulation of SII on the nucleus CM, but is not involved in the regulatory effect of electroacupuncture on the nucleus CM.