Zhen Ci Yan Jiu. 1996 ; 21(4): 22-4.

[The relationship of C fiber to 5-hydroxytryptamine in spinal cord of rat in electroacupuncture analgesia]

Wang L, Li Z, Guan X.

Department of Physicochemistry, School of Pharmacy, Tongji Medical University, Wuhan.

By using spectrofluorophotometry, it was observed that electroacupuntrure at "Huantiao" points of rat could decease the content of 5-hydroxytryptamine (5-HT) and increase the content of 5-hydroxyindoleacetic acid (5-HIAA) in spinal cord. However, the above effects of electroacupunture were obviously reduced after the C fibers of rats had been destroyed by capsaicin, which suggesting that capsaicin-sensitive C fiber might take part in the roles of electroacupuncture's promoting the release and utilization of 5-HT in spinal cord.