Impaired brainstem auditory evoked potentials in patients with cystic fibrosis

Author(s): Tabachnik, E., Shahar, E., Gilai, A.

Journal/Book: Dev Med Child Neurol. 1996; 38: 40 West 20TH Street, New York, NY 10011-4211. Cambridge Univ Press. 59-64.

Abstract: Brainstem auditor Si evoked potentials (BAEPs) were measured in 11 young patients with cystic fibrosis (CF). Though none had clinical evidence of neurological impairment,all had various abnormal components of brainstem auditory evoked potentials (BAEPs). Abnormal BAEPs may be attributed to nutritional deficiencies including deficiencies of vitamins E and B-6. AS patients with CF are often deficient in vitamin E despite daily supplementation and normal serum levels, the authors suggest that the abnormal BAEPs demonstrated in the present study may reflect prolonged intracellular vitamin E deficiency. This finding suggests that BAEP studies may be useful in the neurological evaluation of patients with CF.

Note: Article N Vaisman, Kaplan Hosp, Dept Paediat, Nutr Clin, IL-76100 Rehovot, Israel

Keyword(s): VITAMIN-E-DEFICIENCY; NEUROLOGICAL FUNCTION; CHOLESTASIS; CHILDREN; DISORDERS; RAT

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