Pediatric HIV infection: A review of epidemiology, clinical manifestations, and current intervention

Author(s): Doyle, M. D., Pickering, L. K., Ortegon, J.

Journal/Book: J Dev Phys Disabilities. 1996; 8: 233 Spring St, New York, NY 10013. Plenum Publ Corp. 179-210.

Abstract: Human Immunodeficiency Virus (HIV) infection has emerged as a global epidemic that is predicted to kill many thousands of children by the end of this century. In this review, several aspects of pediatric HIV infection are presented The epidemiology of HIV infection is briefly surveyed in the United States, Africa, Europe, the Caribbean and Asia. Clinical manifestations of pediatric HIV infection, which are not entirely congruent with the signs and symptoms often found in adults, are also reviewed including medical, neurological, developmental, and behavioral manifestations of this disease process. Finally, an intervention program outlining current medical, pharmacological and neurodevelopmental follow-up cave is discussed.

Note: Review VS-Card DA Pearson, Univ Texas, Sch Med, Dept Psychiat & Behav Sci, Houston, TX 77030 USA

Keyword(s): HIV infection; pediatrics; neurodevelopment; epidemiology; antiretroviral treatment; HUMAN-IMMUNODEFICIENCY-VIRUS; IMMUNE-DEFICIENCY SYNDROME; INFUSION ZIDOVUDINE THERAPY; CENTRAL NERVOUS-SYSTEM; TO-CHILD TRANSMISSION; AIDS DEMENTIA COMPLEX; DEVELOPMENTAL ABNORMALITIES; NEURODEVELOPMENTAL FINDINGS; PERINATAL TRANSMISSION; HEMOPHILIA GROWTH

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