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January 2022

Recent developments in the pharmacotherapy of substance abuse

Journal/Book: J Consult Clin Psychol. 1996; 64: 750 First St NE, Washington, DC 20002-4242. Amer Psychological Assoc. 677-686.

Abstract: Modern concepts of addictive disorders emphasize the compulsive and relapsing drug-taking behaviors rather than tolerance and physical dependence. As with any chronic disorder, long-term treatment is necessary and medications may aid in the rehabilitative process. Specific medications have been demonstrated to be helpful for psychiatric disorders coexisting with addiction. Medications have also been demonstrated in controlled studies to aid in the rehabilitation of patients dependent on nicotine, alcohol, or opiates. Thus far, no medication has been clearly demonstrated to benefit patients suffering from abuse or dependence on cocaine, cannabinoids, nonalcohol sedatives, or hallucinogens.

Note: Article CP Obrien, Univ Penn, Philadelphia Vet Affairs Med Ctr, 3900 Chestnut St, Philadelphia, PA 19104 USA

Keyword(s): CANNABINOID RECEPTOR; METHADONE-MAINTENANCE; COCAINE DEPENDENCE; ALCOHOL DEPENDENCE; SMOKING CESSATION; NICOTINE PATCH; NALTREXONE; BRAIN; ABSTINENCE; INPATIENT


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