Hearing loss in multiple sclerosis: Localization of the auditory pathway lesion according to electrocochleographic findings

Journal/Book: J Laryngol Otol. 1996; 110: Invicta Press, Ashford, Kent, England TN24 8HH. Headley Brothers Ltd. 252-257.

Abstract: Multiple sclerosis is known to affect the myelin of the auditory pathway resulting in acute hearing loss. Two cases of sudden deafness due to multiple sclerosis have been evaluated by conventional audiometry, brainstem auditory evoked response audiometry and transtympanic electrocochleography. The abnormalities of the compound action potential in both patients (enhanced latency, abnormal adaptation using fast stimulus rate) and the normal receptor potentials (cochlear microphonic, summating potential), as well as the absence of brainstem responses suggest a disturbance of synchronization at the level of the first auditory neurone. The electrocochleography provides valuable information for the topodiagnosis of this and other neural hearing losses, especially in the absence of reliable brainstem responses.

Note: Article N Marangos, Univ Freiburg, Hno Klin, Killianstr 5, D-79106 Freiburg, Germany

Keyword(s): multiple sclerosis; hearing loss, sensorineural; audiometry, evoked response

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