A randomized controlled prospective outcome study of a psychological and pharmacological intervention protocol for procedural distress in pediatric leukemia

Author(s): Penati, B., Boyer, B. A., Himelstein, B., Brophy, P., Waibel, M. K., Blackall, G. F., Daller, R., Johnson, K.

Journal/Book: J Pediat Psychol. 1996; 21: 233 Spring St, New York, NY 10013. Plenum Publ Corp. 615-631.

Abstract: Evaluated distress during invasive procedures in childhood leukemia. Child and parent distress, assessed by questionnaires and ratings, were compared in two arms of a randomized, controlled prospective study, one a pharmacologic only (PO) (n = 45) and the other a combined pharmacologic and psychological intervention (CI) (n = 47), at 1, 2, and 6 months after diagnosis. The cross sectional control group (CC) consisted of parents of 70 patients in first remission prior to the prospective study. Mothers' and nurses' ratings of child distress indicated less child distress in the CI group than the PO. When contrasted with the CC group, the CI group showed lower levels of child distress, Data showed decreases over time in distress and concurrent improvements in quality of life and parenting stress and supported an inverse association between distress and child age.

Note: Article AE Kazak, Childrens Hosp, Div Oncol, Psychosocial Serv, 324 S 34TH St, Philadelphia, PA 19104 USA

Keyword(s): childhood cancer; medical procedures; child and parent distress; psychological and pharmacological intervention; PAINFUL MEDICAL PROCEDURES; COGNITIVE-BEHAVIOR THERAPY; CHILDREN; ADAPTATION; SYSTEMS; PARENTS; MODEL

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