Am J Chin Med. 1995 ; 23(2): 195-211.

Traditional Chinese medicines improve the course of refractory leukemic lymphoblastic lymphoma and acute lymphocytic leukemia: two case reports.

Hijikata Y, Kaneko J, Xi L, Nasu M, Yamashita S.

Tokyo Adventist Hospital, Japan.

A 34 year-old man with leukemic lymphoblastic lymphoma (LBL), who could not tolerate chemotherapy due to its side effects, was diagnosed to have an acute febrile disease by a traditional Chinese medical doctor, Lu Gan Fu. Zixuedan, a traditional Chinese remedy for dissipation of pathogenic heat and detoxification that could reduce WBC count including leukemic cells below 1000/microliters without intolerable side effects, was prescribed for treatment. A second case of acute lymphocytic leukemia (ALL) was a 41 year-old female who also could not tolerate chemotherapy. In her fourth recurrence, she started Chinese medicine including modified zixuedan, which gave her transient improvement followed by aggravation. Intake of previously ineffective cyclophosphamide in combination with Chinese medicine led to a dramatic improvement.