A new spontaneous allele at the pink-eyed dilution (p) locus discovered in Mus musculus castaneus

Author(s): Wakayama, T., Ishikawa, A.

Journal/Book: Jikken Dobutsu. 1995; 44: 347-51.

Abstract: Mutant mice characterized by a cream coat and pink eyes were spontaneously discovered among the descendants of Indonesian wild mice (Mus musculus castaneus). This mutant phenotype was controlled by a single autosomal recessive gene that was allelic to the pink-eyed dilution (p) gene. The mutant mouse phenotypically resembled the original p mouse which was the first mutant identified at this locus. Nevertheless, these two alleles differed in origin, a previous report suggesting that the original p allele was derived from Japanese wild mice (M. m. molossinus). Thus the symbol pcas (pink-eyed castaneus) was proposed for the present mutation allele.

Keyword(s): Alleles; Mice, Mutant Strains [genetics]

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