Empirically derived subtypes of pervasive developmental disorders: A cluster analytic study

Author(s): Matson, J. L., Coe, D., Love, S. R., Matese, M. J., Benavidez, D. A.

Journal/Book: J Autism Dev Disord. 1995; 25: 233 Spring St, New York, NY 10013. Plenum Publ Corp. 561-578.

Abstract: A cluster analytic study was conducted to empirically derive behaviorally homogeneous subtypes of pervasive developmental disorders (PDD). Subjects were clustered based on a broad range of behavioral symptoms which characterize autism. Behavioral variables were measured using several of the standardized psychometric instruments most commonly employed in assessing autistic individuals. The cluster solution indicated the presence of four distinct groups. Validity checks generally confirmed significant between-group differences on independent measures of social, language, and stereotyped behaviors. In addition, the four-group cluster solution was compared to previously developed typological systems of PDD (i.e., subcategories based on la early onset, styles of social interaction, and DSM-III-R diagnosis). Results generally supported both the behavioral homogeneity of the four subgroups and also several important between-group differences. The potential utility of using cluster analyses to explore subtypes of PDD is discussed.

Note: Article JA Sevin, Se Louisiana Univ, POB 3850, Mandeville, LA 70470 USA

Keyword(s): AUTISM RATING-SCALE; ADAPTIVE-BEHAVIOR SCALES; CHILDHOOD AUTISM; DSM-III; CHILDREN; FENFLURAMINE; CLASSIFICATION; ADOLESCENTS; OUTPATIENTS; DIAGNOSIS

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