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November 2022

Zhen Ci Yan Jiu. 1993 ; 18(1): 64-7.

[The correlation between postsynaptic inhibition and GABA, opioid peptides, SP in electroacupuncture]

Fang Z, Yu Q, Li Y.

Institute of Acupuncture and Moxibustion, China Academy of TCM, Beijing.

Identified tract cells in lumbar enlargement were recorded from intact anaesthetized rats. The prolongation of the latency of antidromic action potential was a measure of postsynaptic inhibition. Both ST 36 and SP 6 were stimulated electrically. In EA group (N = 12) EA prolonged the latency for 0.111 +/- 0.022 ms (P < 0.001). In bicuculline group (N = 12) the prolongation of the latency for 0.010 +/- 0.004 ms (P < 0.05) by EA was less than that of EA group with statistical significance. In naloxone group (N = 12) and SP antiserum group (N = 12) EA did not induce a significant prolongation of the latency. It suggested that GABA, opioides and SP might be involved in postsynaptic inhibition induced by EA.

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