A song in praise of peptide palindromes

Journal/Book: Leukemia. 1993; 7 Suppl 2: S157-9.

Abstract: Peptide palindromes are invariably found in all proteins, and long palindromes exceeding 10 residues in length are not rare. They are particularly abundant in DNA-binding proteins such as H1 histone. When a complementary strand of the coding sequence is translatable being free of a chain terminator, a complementary protein encode by it becomes equally abundant in peptide palindromes. The simultaneous musical transformation of both strands of mouse H1 histone variety-1 DNA enable us to appreciate the symmetrical beauty of successive palindromes appearing in both H1 histone and its complementary protein.

Note: Beckman Research Institute of the City of Hope Duarte Ca 91010-0269.

Keyword(s): Amino Acid Sequence|. Histones|CH. Music|

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