Congress of PhytotherapyMunich 1992 |
Author(s):
, , , ,Abstract: In continuation of the reports in ZPT 14, No. 1 (1993) this article reviews clinical relevant and theoretical results presented at the fourth and International Congress of Phytotherapy 1992 in Munich. Thus flavonoglycosides of Ginkgo biloba extracts seem not to be responsible for their cerebral effects. More likely these effects seem to be related to the PAF-antagonistic ginkgolides A, B and C. The PAF-antagonistic properties (inhibition of PAF-induced aggregation) of the terpenelactones provide a new method for standardization of Ginkgo-extracts. Further the neuroprotective activity of bilobalide and protection of the peripheral nervous system by Ginkgo extract could be demonstrated. - A prospective study on the carcinogenic risk of anthranoid-laxatives revealed an association of pseudo-melanosis coli and colorectal tumors in men. For patients using excessive amounts of laxatives a relative risk of 3.04 (1.18-4.90) for colorectal tumors is calculated. These results are in contrast to those obtained by a retrospective study presented at the Munich Congress. In rats application of daily doses of 5-25 mg/kg of a Senna-preparation for 2 years did not increase the incidence of neoplasia. - The antidepressive effect of hypericum-extracts could be confirmed by clinical studies. - A combination of Primulae radix, Gentianae radix, Verbenae herba, Sambuci flos and Rumicis herba (Sinupret®) in rats revealed an secretion stimulating effect which was as high as that of the classical drugs Hedera helix, Thymus vulgaris and Primula veris. The combination further had a significant stimulating effect on immune parameters. In doubleblind clinical studies Sinupret® increased the bronchial clearance to an even higher degree than synthetic secretolytics.
Keyword(s): Phytotherapy congress Munich 1992
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