Planta Med. 1992 Jun; 58(3): 234-6.

Effect of Galphimia glauca methanolic extract on neuropharmacological tests.

Tortoriello J, Lozoya X.

Traditional Medicine and Drug Development Research Unit, Mexican Institute of Social Security, IMSS.

Galphimia glauca Cav. (Malpighiaceae) is used in Mexican traditional medicine for the treatment of nervous excitement. A methanolic extract from its aerial parts (MEGA) was tested in several neuropharmacological animal models including among others: hypothermic activity, barbiturate potentiation, protection against strychnine- and leptazol-induced convulsions. The combined data obtained from all biological models demonstrate the sedative property of this plant product.