Ned Tijdschr Geneeskd. 1991 Aug; 135(31): 1399-403.

[Polychlorobiphenyls in human milk, adipose tissue, plasma and umbilical cord blood; levels and correlates]

van Kaam AH, Koopman-Esseboom C, Sulkers EJ, Sauer PJ, van der Paauw CG, Tuinstra LG.

Academisch Ziekenhuis Rotterdam-Sophia Kinderziekenhuis, afd. Kindergeneeskunde, subafd. Pasgeborenen.

In a longitudinal study involving 17 women, PCB concentrations (PCBs 138, 153 and 180) were determined in cord blood (17 newborns), breast milk (10 women), maternal adipose tissue (8 women), maternal plasma collected during the last trimester of pregnancy (17 women) and maternal plasma collected 10 days post partum (7 women). Significant correlations were found (p less than 0.05) between PCB levels in cord blood, breast milk and adipose tissue and maternal plasma collected before birth, and between breast milk and maternal plasma collected post partum. In 2 vegetarian women the PCB levels in maternal plasma and cord blood were significantly lower than in the other women (p less than 0.05). If in future studies the PCB levels observed prove to be detrimental to child development, these correlations may offer the possibility of identifying a group of newborns at risk for occurrence of developmental defects due to PCB exposure before birth.