Ned Tijdschr Geneeskd. 1991 Dec; 135(49): 2341-4.

[Acute circulatory shock following administration of the non-regular enzyme preparation Wobe-Mugos]

de Smet PA, Pegt GW, Meyboom RH.

Koninklijke Nederlandse Maatschappij ter bevordering der Pharmacie, Geneesmiddel Informatie Centrum, Gravenhage.

A 54-year-old female patient was treated by a homoeopathic physician with non-orthodox enzyme therapy because of complaints pointing to multiple sclerosis. The therapy consisted of courses of German enzyme preparations (Wobe-Mugos injections, Wobenzym tablets and Wobe-Mugos suppositories), each of which lasted three weeks. During the third course the patient developed a circulatory shock immediately following an injection. She recovered successfully in hospital. On inquiry it became evident that symptoms of tightness, light-headedness and dry mouth had already occurred after a previous injection. In connection with this case a table is presented which reviews the alternative therapies that have been associated with anaphylactic or anaphylactoid reactions.