Farmakol Toksikol. 1991 Sep-Oct; 54(5): 12-3.

[The combined use of acupuncture and antidepressants for managing the spondylogenic lumbosacral pain syndrome]

Amelin AV, Vasil'ev IuN, Ignatov IuD, Skoromets AA.

The effects of antidepressants amitriptyline and pyrazidol on the analgesic action of acupuncture in patients with lumbosacral radiculitis was studied by the double blind control method. The combined use of acupuncture with antidepressants was shown to enhance the effectiveness of the treatment, to increase on the average by 5-6 hours the duration of analgesia within 24 hours after each procedure, to reduce the duration of the treatment on the average by 4-5 days, that indicates the expediency of clinical use of the proposed combination.