Ginkgo-biloba-Spezialextrakt bei Patienten mit hirnorganischem Psychosyndrom - Prüfung der Wirksamkeit mit neurophysiologischen und psychometrischen Methoden

Journal/Book: Münchener Medizinische Wochenschrift; in press. 1991; (Suppl.): 30-33.

Abstract: Ginkgo Biloba Special Extract Treatment ii Patients with Cerebro-organic Syndrome Study an the Efficacy with Neurophysiological and Psychometrical Methods: 50 inpatients aged 57 to 76 years with cerebro-organic syndrome from a neurological department participated in a placebo-controlled double-blind trial to study the efficacy of the Ginkgo biloba special extract LI 1370. After washout phase of 14 days, 6 weeks of therapy with the intake of 3 x 1 coated tablet followed according to a daily dosage of 15i mg of verum treatment. The therapeutic efficacy was tested with 2 psychometrical test (Vienna Determination Test and Figur Connection Test) and 3 neurophysiological methods of measurement (saccadic eye movements, EEG analysis and measurement of the evoked potentials). For all 5 target criteria' a statisticallly highly significant superiority of active treatment (p < 0,001) was shown in comparison to the placebo group, which appeared only after 3 weeks of therapy and became more obvious after 6 weeks. At the same time the clinical symptoms improved. The results show that therapy with the Ginkgo biloba special extract LI 1370 in patients with cerebro-organic Syndrome contributes to an increased cerebral capacity.

Keyword(s): Ginkgo biloba

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