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J Nat Prod. 1990 Sep-Oct; 53(5): 1212-9.

Chemical studies on Mexican plants used in traditional medicine, XV. Sesquiterpene evoninoate alkaloids from Hippocratea excelsa.

Mata R, Calzada F, Díaz E, Toscano RA.

División de Bioquímica y Farmacia, Facultad de Química, Ciudad Universitaria, México D.F.

Three sesquiterpene evoninoate alkaloids, hippocrateine I [1], hippocrateine II [2], and emarginatine A have been isolated from the root and stem barks of Hippocratea excelsa. Compounds 1 and 2 are new naturally occurring substances. The structure of 1 was unequivocally established by X-ray crystallographic analysis, and the structure of the second new alkaloid was deduced by spectral analysis.


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