J Ethnopharmacol. 1990 Sep; 30(2): 157-68.

Ethnopharmacology of rhinoceros horn. I: Antipyretic effects of rhinoceros horn and other animal horns.

But PP, Lung LC, Tam YK.

Department of Biology, Chinese University of Hong Kong, Shatin, N.T.

Intraperitoneal administration of an aqueous extract of rhinoceros horn at 5, 2.5 and 1 g/ml, showed a significant antipyretic effect in rats with hyperthermia induced by subcutaneous injection of terpentine oil. Similar assays with extracts of the horns of saiga antelope, water buffalo and cattle at 5 g/ml also caused a significant drop in fever; however, at 1 g/ml, only saiga antelope horn produced an antipyretic action.