Zhong Xi Yi Jie He Za Zhi. 1989 Jan; 9(1): 10-3, 3-4.

[The relation of lesions of the testis and acute injury and chronic disease of the kidney]

Kuang DY.

In this paper, the testicular routine sections of ninety autopsy cases of males between 20 and 29 years old were studied. The autopsies were performed in the department of pathology at the Bowman Gray School of Medicine of Wake Forest University in the United States. Primary pathological diagnoses were divided into acute injury (63 cases) and chronic disease (27 cases) groups. Using the following criteria, the authors divided the testicular changes into three stages: (1) The early stage (about 4th day): There was slight sloughing and disorganization of the germinal epithelium. Acute group occurred 43 cases, chronic 6 cases. (2) The middle stage (about 15th day): The basement membrane of the tubules was slightly thickened. Sloughing, disorganization and degenerative changes of various germinal cells were obvious. Giant cell formation was present. Acute group occurred 17 cases, chronic 8 cases. (3) The late stage (longer than 25 days): The diameter of the testicular tubules was obviously reduced, the basement membrane was very thickened; various germinal cells disappeared. Only Sertoli cells or just hyalinized fibrous tissues were seen. Interstitial fibrosis and Leydig cells were atrophied. These results indicated that the longer the duration, the serious the lesions. Based on the results of the above observation, the authors emphasize that the lesions of the reproductive glands play an important role in the pathogenesis of disease. It is reasonable in believing that we should use drugs or herbs which might help and protect the "Shen" and Semen for the treatment of the patients as early as possible, no matter whether or not they have sexuality impaired.