Knollenblätterpliz-Intoxikationen: Übersicht und Falldiskussion

Author(s): Weilemann, L.

Journal/Book: Intensivmed. 1989; 26: 354-359.

Abstract: First step of therapy of amanita mushroom poisoning is to avoid further toxin absorption. In the specific antidote therapy, drugs with clear proven effectiveness should have priority. These are silibinin and penicillin G while, however, the therapeutic effect of other betalactam-antibiotics in comparison of penicillin G has to be evaluated. Special attention has to be directed to the blood coagulation system and here peculiar to antithrombin III. We prefer hemoperfusion as a method of extracorporal toxin elimination especially, when it has alredy come to a progrediet hepatic coma. Still the most important part of treatment is a sufficient gastric lavage, the removal of noxious toxic factor by charcoal in addition with well established drugs.

Keyword(s): Amatoxine

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