3 monatige, randomisierte doppelblinde Dosis-Wirkungsstudie mit O-(Beta-Hydroxyäthyl)-rutosid-Trinklösung

Author(s): Diebschlag, W., Lehmacher, W.

Journal/Book: VASA. 1989; 18: 235-238.

Abstract: The antioedematous effect of 0-(ß-Hydroxylethyl)-rutoside (HR)-drinking solutions with 600, 900, 1200 and 1500 mg active substance was tested in a randomized double-blind study against placebo with 30 female patients in the change of life. The decrease of the oedemas was measured by recording the change in the leg volume. The patients valued the symptoms <<tired and heavy legs> > , <<tenseness)) and «tingling sensation». After 3 months the daily taking of HR-drinking solutions showed a significant decrease of leg volume. At the end of the treatment there was no significant difference between the four verum groups.

Keyword(s): Doppelblinde Dosis-Wirkungsstudie

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